高级中间体
Name |
Structure |
CAS No. |
阿托伐他汀钙中间体A5 |
ethyl (R)-4-cyano-3-hydroxybutanoate |
141942-85-0 |
阿托伐他汀钙中间体A6 |
tert-butyl (R)-6-cyano-5-hydroxy-3-oxohexanoate |
125988-01-4 |
阿托伐他汀钙中间体A7 |
tert-butyl (3R,5R)-6-cyano-3,5-dihydroxyhexanoate |
125971-93-9 |
阿托伐他汀钙中间体A8 |
tert-butyl 2-((4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl) acetate |
125971-94-0 |
阿托伐他汀钙中间体A9 |
tert-butyl2-((4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl) acetate |
125995-13-3 |
阿托伐他汀钙中间体M4 |
2-(2-(4-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenyl- pentanamide |
125971-96-2 |
阿托伐他汀钙中间体L1 |
tert-butyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- (phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl) acetate |
125971-95-1 |
阿托伐他汀钙中间体L2 |
tert-butyl (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenyl carbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate |
134395-00-9 |
阿托伐他汀钙L4(API) |
Atorvastatin Calcium |
134523-03-8 |
瑞舒伐他汀钙中间体RSB-2 |
methyl 4-(4-fluorophenyl)-6-isopropyl-2-oxo-1,2,3,4-tetrahydro- pyrimidine-5-carboxylate |
488798-36-3 |
瑞舒伐他汀钙中间体RSB-3 |
methyl 4-(4-fluorophenyl)-2-hydroxy-6- isopropyl- pyrimidine -5-carboxylate |
488798-37-4 |
瑞舒伐他汀钙中间体RSB-4 |
methyl 4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)- pyrimidine-5-carboxylate |
289042-11-1 |
瑞舒伐他汀钙中间体Z-7 |
N-(4-(4-fluorophenyl)-5-(hydroxymethyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide |
147118-36-3 |
瑞舒伐他汀钙中间体Z8.1 |
N-(5-((diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide |
289042-10-0 |
瑞舒伐他汀钙中间体Z8.2 |
Phosphonium, [[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]me |
885477-83-8 |
瑞舒伐他汀钙中间体D-4 |
tert-butyl 2-((4R,6S)-6-(chloromethyl)-2,2-dimethyl-1,3- dioxan-4-yl)- acetate |
154026-94-5 |
瑞舒伐他汀钙中间体D-5 |
tert-butyl 2-((4R,6S)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4- yl)acetate |
154026-95-6 |
瑞舒伐他汀钙中间体D-6 |
tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3- dioxan-4-yl) acetate |
124655-09-0 |
瑞舒伐他汀钙中间体D-7 |
tert-butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate |
124752-23-4 |
瑞舒伐他汀钙中间体Z-8 |
N-(4-(4-fluorophenyl)-5-formyl-6-isopropylpyrimidin-2-yl)-N-methyl- methanesulfonamide |
147118-37-4 |
瑞舒伐他汀钙中间体R-1 |
tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl) amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3- dioxane-4-acetate |
289042-12-2 |
瑞舒伐他汀钙中间体R-2 |
tert-Butyl rosuvastatin |
355806-00-7 |
瑞舒伐他汀钙中间体H-1 |
methyl (R,E)-3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6- isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-oxohept- 6-enoate |
147118-38-5 |
瑞舒伐他汀钙中间体H-2 |
7-[4-fluorophenyl]-6-isopropyl)-2-(N-Methyl-N-MethylSulfonyl amino) pyrimidine -5-yl]-(3R)-3-(terbutyldimethylsilyloxy)-5-oxo-6E-heptane acid,Methyl ester |
147118-39-6 |
瑞舒伐他汀钙中间体H-3 |
methyl (E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl) amino]-6-propan -2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate |
147118-40-9 |
瑞舒伐他汀钙RS(API) |
Rosuvastatin Calcium |
147098-20-2 |
匹伐他汀钙中间体N7 |
(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)methanol |
121660-11-5 |
匹伐他汀钙中间体N7-Br |
3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline |
154057-56-4 |
匹伐他汀钙中间体N8.1 |
((2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)methyl)diphenylphosphine oxide |
146578-99-6 |
匹伐他汀钙中间体P1 |
tert-butyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate |
147489-06-3 |
匹伐他汀钙中间体P2 |
tert-butyl (3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate |
586966-54-3 |
匹伐他汀钙中间体N8.2 |
[2-Cyclopropyl-4-(4-fluorophenyl)-quinolin-3-ylmethyl]-triphenyl-phosphonium bromido |
154057-58-6 |
匹伐他汀钙中间体N8 |
2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde |
121660-37-5 |
匹伐他汀钙中间体K2 |
ethyl (E)-3-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylate |
2101241-52-3 |
匹伐他汀钙中间体K3 |
(E)-3-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)prop-2-en-1-ol |
1623109-08-9 |
匹伐他汀钙中间体K4 |
(E)-3-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylaldehyde |
148901-68-2 |
匹伐他汀钙中间体K5 |
ethyl (E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-5-hydroxy- |
148901-69-3 |
3-oxohept-6-enoate |
||
匹伐他汀钙中间体K6 |
Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoate |
172336-32-2 |
477950-34-8 |
||
匹伐他汀钙PI (API) |
Pitavastatin Calcium |
147526-32-7 |
匹伐他汀钙中间体D-5 |
tert-butyl 2-((4R,6S)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4- yl)acetate |
154026-95-6 |
匹伐他汀钙中间体D-6 |
tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3- dioxan-4-yl) acetate |
124655-09-0 |
匹伐他汀钙中间体D-7 |
tert-butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate |
124752-23-4 |
索弗布韦中间体SFA-9 |
((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran- 2- yl) methyl benzoate |
874638-80-9 |
索弗布韦中间体SFC |
isopropyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate |
1334513-02-8 |
索弗布韦中间体SF-1 |
(2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy) methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate |
817204-32-3 |
索弗布韦中间体SF-2 |
((2R,3R,4R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate |
863329-65-1 |
索弗布韦中间体SF-3 |
2'-deoxy-2'-fluoro-2'-C-methyluridine |
863329-66-2 |
依折麦布中间体ZTM |
4-(((4-fluorophenyl)imino)methyl)phenol |
3382-63-6 |
依折麦布中间体ZT-4 |
(S)-1-(4-fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5- dione |
189028-93-1 |
依折麦布中间体ZT-5 |
(S)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2 -one |
189028-95-3 |
依折麦布中间体ZT-6 |
(S)-3-((2R,5S)-5-(4-fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one |
272778-12-8 |
依折麦布中间体ZT-7 |
(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one |
272778-13-9 |
依折麦布中间体ZTB-7 |
(3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one |
190595-65-4 |
依折麦布中间体ZTB-8 |
4'-O-Benzyloxy Ezetimibe |
163222-32-0 |
达比加群中间体DB-6 |
ethyl 3-(2-(((4-cyanophenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)- 1H- benzo[d]imidazole-5-carboxamido)propanoate |
211915-84-3 |
达比加群中间体DB-7 |
1-methyl-2-[N-[4-amidinophenyl]aminomethyl]benzimidazol-5-yl-carboxylicacid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide para-toluene sulfonate |
872728-85-3 |
达比加群中间体DB-7-1 |
ethyl 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole -5-carbonyl]-pyridin-2-ylamino] propanoate |
429658-95-7 |
达比加群中间体DB-7-2 |
ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate hydrochloride |
211914-50-0 |
达比加群中间体DB-8 |
ethyl 3-(2-(((4-(N-((hexyloxy)carbonyl)carbamimidoyl)phenyl) amino) methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate |
211915-06-9 |
其他中间体DBP |
3-Pyridyldiethylborane |
89878-14-8 |
其他中间体MDEB |
Methoxydiethylborane in THF |
7397-46-8 |
其他中间体-3OT | (S)-(+)-3-Hydroxytetrahydrofuran | 86087-23-2 |
EG4 |
(S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran |
915095-94-2 |
EG4-Br |
(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran |
915095-89-5 |
EG3 |
(S)-(2-Chloro-5-iodophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone |
915095-87-3 |
EG3-Br | (5-bromo-2-chlorophenyl)-[4-[(3S)-oxolan-3-yl]oxyphenyl]methanone | 915095-86-2 |
EG2 |
(2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone |
915095-86-2 |
EG2-Br |
(5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone |
915095-85-1 |
EG1 |
2-Chloro-5-iodobenzoic acid |
19094-56-5 |
EG1-Br |
5-Bromo-2-Chlorobenzoic Acid |
21739-92-4 |
S-3-羟基四氢呋喃(S3) |
(S)-(+)-3-Hydroxytetrahydrofuran |
86087-23-2 |
溴吡喃葡萄糖Piv (EGM-Piv) |
[(2S,3S,4S,5R,6S)-6-bromo-3,4,5-tris(2,2-dimethylpropanoyloxy)tetrahydropyran-2-yl]methyl 2,2-dimethylpropanoate |
81058-27-7 |
葡萄糖酸内酯TMS (EGM-TMS) |
(3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-(trimethylsilyloxymethyl)oxan-2-one |
32384-65-9 |
高级中间体EG5-OMe |
(2S,3R,4S,5S,6R)-2-(3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxyMethyl)-2-Methoxy-2H-pyran-3,4,5-triol |
1279691-36-9 |