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高级中间体

Name

Structure

CAS No.

阿托伐他汀钙中间体A5

ethyl (R)-4-cyano-3-hydroxybutanoate

141942-85-0

阿托伐他汀钙中间体A6

tert-butyl (R)-6-cyano-5-hydroxy-3-oxohexanoate

125988-01-4

阿托伐他汀钙中间体A7

tert-butyl (3R,5R)-6-cyano-3,5-dihydroxyhexanoate

125971-93-9

阿托伐他汀钙中间体A8

tert-butyl 2-((4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl) acetate

125971-94-0

阿托伐他汀钙中间体A9

tert-butyl2-((4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl) acetate

125995-13-3

阿托伐他汀钙中间体M4

2-(2-(4-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenyl- pentanamide

125971-96-2

阿托伐他汀钙中间体L1

tert-butyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- (phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl) acetate

125971-95-1

阿托伐他汀钙中间体L2

tert-butyl (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenyl carbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate

134395-00-9

阿托伐他汀钙L4API

Atorvastatin Calcium

134523-03-8

瑞舒伐他汀钙中间体RSB-2

methyl 4-(4-fluorophenyl)-6-isopropyl-2-oxo-1,2,3,4-tetrahydro- pyrimidine-5-carboxylate

488798-36-3

瑞舒伐他汀钙中间体RSB-3

methyl 4-(4-fluorophenyl)-2-hydroxy-6- isopropyl- pyrimidine -5-carboxylate

488798-37-4

瑞舒伐他汀钙中间体RSB-4

methyl 4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)- pyrimidine-5-carboxylate

289042-11-1

瑞舒伐他汀钙中间体Z-7

N-(4-(4-fluorophenyl)-5-(hydroxymethyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

147118-36-3

瑞舒伐他汀钙中间体Z8.1

N-(5-((diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

289042-10-0

瑞舒伐他汀钙中间体Z8.2

Phosphonium, [[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]me

885477-83-8

瑞舒伐他汀钙中间体D-4

tert-butyl 2-((4R,6S)-6-(chloromethyl)-2,2-dimethyl-1,3- dioxan-4-yl)- acetate

154026-94-5

瑞舒伐他汀钙中间体D-5

tert-butyl 2-((4R,6S)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4- yl)acetate

154026-95-6

瑞舒伐他汀钙中间体D-6

tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3- dioxan-4-yl) acetate

124655-09-0

瑞舒伐他汀钙中间体D-7

tert-butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate

124752-23-4

瑞舒伐他汀钙中间体Z-8

N-(4-(4-fluorophenyl)-5-formyl-6-isopropylpyrimidin-2-yl)-N-methyl- methanesulfonamide

147118-37-4

瑞舒伐他汀钙中间体R-1

tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl) amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3- dioxane-4-acetate

289042-12-2

瑞舒伐他汀钙中间体R-2

tert-Butyl rosuvastatin

355806-00-7

瑞舒伐他汀钙中间体H-1

methyl (R,E)-3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6- isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-oxohept- 6-enoate

147118-38-5

瑞舒伐他汀钙中间体H-2

7-[4-fluorophenyl]-6-isopropyl)-2-(N-Methyl-N-MethylSulfonyl amino) pyrimidine -5-yl]-(3R)-3-(terbutyldimethylsilyloxy)-5-oxo-6E-heptane acid,Methyl ester

147118-39-6

瑞舒伐他汀钙中间体H-3

methyl (E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl) amino]-6-propan -2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate

147118-40-9

瑞舒伐他汀钙RSAPI

Rosuvastatin Calcium

147098-20-2

匹伐他汀钙中间体N7

(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)methanol

121660-11-5

匹伐他汀钙中间体N7-Br

3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline

154057-56-4

匹伐他汀钙中间体N8.1

((2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)methyl)diphenylphosphine oxide

146578-99-6

匹伐他汀钙中间体P1

tert-butyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

147489-06-3

匹伐他汀钙中间体P2

tert-butyl (3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate

586966-54-3

匹伐他汀钙中间体N8.2

[2-Cyclopropyl-4-(4-fluorophenyl)-quinolin-3-ylmethyl]-triphenyl-phosphonium bromido

154057-58-6

匹伐他汀钙中间体N8

2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde

121660-37-5

匹伐他汀钙中间体K2

ethyl (E)-3-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylate

2101241-52-3

匹伐他汀钙中间体K3

(E)-3-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)prop-2-en-1-ol

1623109-08-9

匹伐他汀钙中间体K4

(E)-3-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylaldehyde

148901-68-2

匹伐他汀钙中间体K5

ethyl (E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-5-hydroxy-

148901-69-3

3-oxohept-6-enoate

匹伐他汀钙中间体K6

Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoate

172336-32-2

477950-34-8

匹伐他汀钙PI (API)

Pitavastatin Calcium

147526-32-7

匹伐他汀钙中间体D-5

tert-butyl 2-((4R,6S)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4- yl)acetate

154026-95-6

匹伐他汀钙中间体D-6

tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3- dioxan-4-yl) acetate

124655-09-0

匹伐他汀钙中间体D-7

tert-butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate

124752-23-4

索弗布韦中间体SFA-9

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran- 2- yl) methyl benzoate

874638-80-9

索弗布韦中间体SFC

isopropyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate

1334513-02-8

索弗布韦中间体SF-1

(2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy) methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate

817204-32-3

索弗布韦中间体SF-2

((2R,3R,4R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate

863329-65-1

索弗布韦中间体SF-3

2'-deoxy-2'-fluoro-2'-C-methyluridine

863329-66-2

依折麦布中间体ZTM

4-(((4-fluorophenyl)imino)methyl)phenol

3382-63-6

依折麦布中间体ZT-4

(S)-1-(4-fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5- dione

189028-93-1

依折麦布中间体ZT-5

(S)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2 -one

189028-95-3

依折麦布中间体ZT-6

(S)-3-((2R,5S)-5-(4-fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one

272778-12-8

依折麦布中间体ZT-7

(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one

272778-13-9

依折麦布中间体ZTB-7

(3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one

190595-65-4

依折麦布中间体ZTB-8

4'-O-Benzyloxy Ezetimibe

163222-32-0

达比加群中间体DB-6

ethyl 3-(2-(((4-cyanophenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)- 1H- benzo[d]imidazole-5-carboxamido)propanoate

211915-84-3

达比加群中间体DB-7

1-methyl-2-[N-[4-amidinophenyl]aminomethyl]benzimidazol-5-yl-carboxylicacid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide para-toluene sulfonate

872728-85-3

达比加群中间体DB-7-1

ethyl 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole -5-carbonyl]-pyridin-2-ylamino] propanoate

429658-95-7

达比加群中间体DB-7-2

ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate hydrochloride

211914-50-0

达比加群中间体DB-8

ethyl 3-(2-(((4-(N-((hexyloxy)carbonyl)carbamimidoyl)phenyl) amino) methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate

211915-06-9

其他中间体DBP

3-Pyridyldiethylborane

89878-14-8

其他中间体MDEB

Methoxydiethylborane in THF

7397-46-8

其他中间体-3OT (S)-(+)-3-Hydroxytetrahydrofuran 86087-23-2
EG4

(S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran

915095-94-2
EG4-Br

(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran

915095-89-5
EG3

(S)-(2-Chloro-5-iodophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone

915095-87-3
EG3-Br (5-bromo-2-chlorophenyl)-[4-[(3S)-oxolan-3-yl]oxyphenyl]methanone 915095-86-2
EG2

(2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone

915095-86-2
EG2-Br

(5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone

915095-85-1
EG1

2-Chloro-5-iodobenzoic acid

19094-56-5
EG1-Br

5-Bromo-2-Chlorobenzoic Acid

21739-92-4
S-3-羟基四氢呋喃(S3)

(S)-(+)-3-Hydroxytetrahydrofuran

86087-23-2

溴吡喃葡萄糖Piv

(EGM-Piv)

[(2S,3S,4S,5R,6S)-6-bromo-3,4,5-tris(2,2-dimethylpropanoyloxy)tetrahydropyran-2-yl]methyl 2,2-dimethylpropanoate

81058-27-7

葡萄糖酸内酯TMS

(EGM-TMS)

(3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-(trimethylsilyloxymethyl)oxan-2-one

32384-65-9
高级中间体EG5-OMe

(2S,3R,4S,5S,6R)-2-(3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxyMethyl)-2-Methoxy-2H-pyran-3,4,5-triol

1279691-36-9